Effects of Helicobacter pylori Infection on the Development of Chronic Gastritis.

ABSTRACT:

Background/aims

Based on the gene expression profiles of gastric epithelial tissue at different stages of Helicobacter pylori-infected gastritis, key long noncoding RNAs and genes in the development of Helicobacter pylori infection-induced gastritis were screened to provide a basis for early diagnosis and treatment.

Materials and methods

We downloaded 2 sets of sample data from the database, including gastric epithelial tissue samples from gastritis patients from Bhutan and Dominican, and screened mRNAs in the differentially expressed RNAs of the 2 regions. Mfuzz clustering algorithm was used to screen RNAs related to the 3 stages of chronic gastritis. The competing endogenous RNA (ceRNA) regulation network was constructed, and the selected key RNAs were verified. Samples fr

SUBMITTER: Zhou X 

PROVIDER: S-EPMC10441145 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature