Within-Individual Organization of the Human Cerebral Cortex: Networks, Global Topography, and Function.

ABSTRACT: The human cerebral cortex is populated by specialized regions that are organized into networks. Here we estimated networks using a Multi-Session Hierarchical Bayesian Model (MS-HBM) applied to intensively sampled within-individual functional MRI (fMRI) data. The network estimation procedure was initially developed and tested in two participants (each scanned 31 times) and then prospectively applied to 15 new participants (each scanned 8 to 11 times). Detailed analysis of the networks revealed a global organization. Locally organized first-order sensory and motor networks were surrounded by spatially adjacent second-order networks that also linked to distant regions. Third-order networks each possessed regions distributed widely throughout association cortex. Moreover, regions of distinct t

SUBMITTER: Du J 

PROVIDER: S-EPMC10441314 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature