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ABSTRACT: Background
Early in the pandemic, the United States population experienced a sharp rise in the prevalence rates of opioid use, social isolation, and pain interference. Given the high rates of pain reported by patients on medication for opioid use disorder (MOUD), the pandemic presented a unique opportunity to disentangle the relationship between opioid use, pain, and social isolation in this high-risk population. We tested the hypothesis that pandemic-induced isolation would partially mediate change in pain interference levels experienced by patients on MOUD, even when controlling for baseline opioid use. Such work can inform the development of targeted interventions for a vulnerable, underserved population.Methods
Analyses used data from a cluster randomized trial (N = 188
SUBMITTER: Frohe T
PROVIDER: S-EPMC10441456 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature