Effects of gut microbial therapy on lipid profile in individuals with non-alcoholic fatty liver disease: an umbrella meta-analysis study

ABSTRACT:

Background

Non-alcoholic fatty liver disease (NAFLD), the most common liver disease, is closely associated with metabolic conditions such as obesity and diabetes mellitus, which significantly impact human health outcomes. The impaired lipid profiles observed in NAFLD individuals can further contribute to cardiovascular events. Despite the high prevalence of NAFLD, there is currently no confirmed intervention approved for its treatment. This study aimed to summarize the results of meta-analysis studies of randomized control trials assessing the impact of gut microbial therapy (probiotics, synbiotics, and prebiotics) on the lipid profile of individuals with NAFLD.

Methods

A systematic search was conducted on PubMed, Scopus, Web of Science, and Cochrane Library up to Novembe

SUBMITTER: Naghipour A 

PROVIDER: S-EPMC10441764 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature