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WMel Wolbachia alters female post-mating behaviors and physiology in the dengue vector mosquito Aedes aegypti.


ABSTRACT: Globally invasive Aedes aegypti disseminate numerous arboviruses that impact human health. One promising method to control Ae. aegypti populations is transinfection with Wolbachia pipientis, which naturally infects ~40-52% of insects but not Ae. aegypti. Transinfection of Ae. aegypti with the wMel Wolbachia strain induces cytoplasmic incompatibility (CI), allows infected individuals to invade native populations, and inhibits transmission of medically relevant arboviruses by females. Female insects undergo post-mating physiological and behavioral changes-referred to as the female post-mating response (PMR)-required for optimal fertility. PMRs are typically elicited by male seminal fluid proteins (SFPs) transferred with sperm during mating but can be modified by other factors, including micr

SUBMITTER: Osorio J 

PROVIDER: S-EPMC10442437 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature