Poroelastic behavior and water permeability of human skin at the nanoscale.

ABSTRACT: Topical skin care products and hydrating compositions (moisturizers or injectable fillers) have been used for years to improve the appearance of, for example facial wrinkles, or to increase "plumpness". Most of the studies have addressed these changes based on the overall mechanical changes associated with an increase in hydration state. However, little is known about the water mobility contribution to these changes as well as the consequences to the specific skin layers. This is important as the biophysical properties and the biochemical composition of normal stratum corneum, epithelium, and dermis vary tremendously from one another. Our current studies and results reported here have focused on a novel approach (dynamic atomic force microscopy-based nanoindentation) to quantify biophysica

SUBMITTER: Oftadeh R 

PROVIDER: S-EPMC10443659 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature