Colorectal cancer among inflammatory bowel disease patients: risk factors and prevalence compared to the general population.

ABSTRACT:

Background

Colorectal cancer (CRC) is a feared complication of inflammatory bowel disease (IBD). We aimed to investigate the prevalence and risk factors of CRC among a large cohort of IBD patients.

Methods

Data on IBD patients free of CRC at baseline was extracted using the MDClone platform of the Clalit health maintenance organization in Israel. We investigated the frequency rate of CRC among IBD patients compared to a control group without IBD. Possible risk factors, including comorbidities and IBD-related medications, were investigated in a multivariate analysis.

Results

During a follow-up of 139,448 years among Crohn's disease (CD) patients and 139,533 years among ulcerative colitis (UC) patients, a frequency rate of CRC was 1.5% (191) among 12,888 CD patients and

SUBMITTER: Abu-Freha N 

PROVIDER: S-EPMC10443703 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature