Ontology highlight
ABSTRACT:
SUBMITTER: Kocaturk B
PROVIDER: S-EPMC10443810 | biostudies-literature | 2023 Jul
REPOSITORIES: biostudies-literature
Kocatürk Begüm B Lee Youngho Y Nosaka Nobuyuki N Abe Masanori M Martinon Daisy D Lane Malcolm E ME Moreira Debbie D Chen Shuang S Fishbein Michael C MC Porritt Rebecca A RA Franklin Bernardo S BS Noval Rivas Magali M Arditi Moshe M
JCI insight 20230724 14
Kawasaki disease (KD) is the leading cause of acquired heart disease among children. Increased platelet counts and activation are observed during the course of KD, and elevated platelet counts are associated with higher risks of developing intravenous immunoglobulin resistance and coronary artery aneurysms. However, the role of platelets in KD pathogenesis remains unclear. Here, we analyzed transcriptomics data generated from the whole blood of patients with KD and discovered changes in the expr ...[more]