Fecal calprotectin level in microscopic colitis: a systematic review and meta-analysis.

ABSTRACT:

Background

There are no specific biomarkers for microscopic colitis (MC), and the diagnosis depends on histopathological tissue obtained during colonoscopy. Studies on the role of fecal calprotectin (FCP) in MC are limited. A literature search of PubMed, Embase, and Scopus was conducted from each database's inception through September 2022.

Methods

A DerSimonian-Liard random-effects meta-analysis was performed to examine the standardized mean difference (SMD) in FCP levels between patients with MC and control patients with chronic diarrhea.

Results

Six studies with 96 active MC patients and 200 controls were included in the meta-analysis. Random effects meta-analysis revealed that FCP was significantly and moderately elevated in patients with MC compared to the contro

SUBMITTER: Songtanin B 

PROVIDER: S-EPMC10444001 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature