Parallel multi-droplet platform for reaction kinetics and optimization.

ABSTRACT: We present an automated droplet reactor platform possessing parallel reactor channels and a scheduling algorithm that orchestrates all of the parallel hardware operations and ensures droplet integrity as well as overall efficiency. We design and incorporate all of the necessary hardware and software to enable the platform to be used to study both thermal and photochemical reactions. We incorporate a Bayesian optimization algorithm into the control software to enable reaction optimization over both categorical and continuous variables. We demonstrate the capabilities of both the preliminary single-channel and parallelized versions of the platform using a series of model thermal and photochemical reactions. We conduct a series of reaction optimization campaigns and demonstrate rapid acquisit

SUBMITTER: Eyke NS 

PROVIDER: S-EPMC10445457 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature