Characteristics of immunotherapy trials for nasopharyngeal carcinoma over a 15-year period.

ABSTRACT:

Background

Immunotherapy has been a hotspot in nasopharyngeal carcinoma (NPC) in recent years. This study aimed to provide a comprehensive landscape of the characteristics of immunotherapy clinical trials in NPC and to determine whether contemporary studies are of sufficient quality to demonstrate therapeutic value.

Methods

This is a cross-sectional analysis of NPC trials registered on ClinicalTrials.gov in the last 15 years (Jan 1, 2008-Nov 20, 2022). Only interventional trials with a primary purpose of treatment were included in the final analysis. Characteristics of immunotherapy trials were compared with those of other NPC trials. Chronological shifts in NPC immunotherapy trials were also analyzed.

Results

Of the 440 NPC studies selected, 161 (36.6%) were immunoth

SUBMITTER: Huang H 

PROVIDER: S-EPMC10445486 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature