Cold Spells and the Onset of Acute Myocardial Infarction: A Nationwide Case-Crossover Study in 323 Chinese Cities.

ABSTRACT:

Background

Few studies have explored the relationships between cold spells and acute myocardial infarction (AMI) using the information of symptom onset.

Objectives

We assessed the impact of cold spells on AMI onset and the potential effect modifiers.

Methods

We conducted a time-stratified case-crossover study among 456,051 eligible patients with AMI from 2,054 hospitals in 323 Chinese cities between January 2015 and June 2021 during cold seasons (November to March). Nine definitions of cold spells were used by combining three relative temperature thresholds (i.e., lower than the 7.5th, 5th, and 2.5th percentiles) and three durations of at least 2-4 consecutive d. Conditional logistic regressions with distributed lag models were applied to evaluate the cumulated effect

SUBMITTER: Jiang Y 

PROVIDER: S-EPMC10445528 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature