RBM10: Structure, functions, and associated diseases.
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ABSTRACT:
SUBMITTER: Inoue A
PROVIDER: S-EPMC10445532 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Publications
RBM10 is a nuclear RNA-binding protein (RBP) that regulates the alternative splicing of primary transcripts. Recently, research on RBM10 has become increasingly active owing to its clinical importance, as indicated by studies on RBM0 mutations that cause TARP syndrome, an X-linked congenital pleiotropic developmental anomaly, and various cancers such as lung adenocarcinoma in adults. Herein, the molecular biology of RBM10 and its significance in medicine are reviewed, focusing on the gene and pr ...[more]
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