Test performance of lateral flow rapid antigen tests for COVID-19 in Welsh adult care home staff using routine surveillance data.

ABSTRACT:

Background

Lateral flow tests (LFTs) have been used to screen for SARS-CoV2 in Wales since January 2021. Between May and August 2021, adult care home staff policy was for biweekly Innova LFT and weekly Polymerase Chain Reaction (PCR) testing while asymptomatic. We estimated test performance of LFTs conducted in adult care home staff using PCR tests as a reference standard.

Methods

Test results from surveillance data were matched by individual where both LFT and PCR were taken on the same day. We calculated sensitivity, specificity, positive and negative predictive values, and agreement using Matthew's correlation coefficient. Ct values of positive PCR results were compared by matched LFT result. Analysis was conducted using R v4.1.3.

Results

We analysed 115,593 test p

SUBMITTER: Hogg C 

PROVIDER: S-EPMC10446167 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature