Circulating foot-and-mouth disease virus serotype A African-genotype IV in Egypt during 2022.

ABSTRACT:

Background and aim

Foot-and-mouth disease (FMD) virus causes continuous outbreaks, leading to serious economic consequences that affect animal productivity and restrict trade movement. The potential influence of the disease was due to the emergence of new strains or re-emergence of local strains with major antigenic variations due to genetic mutations. This study aims to evaluate circulating virus in samples collected from infected animals during an outbreak using antigenic characterization and identify whether there is an emergence of a new strain or mutation.

Materials and methods

Reverse-transcription polymerase chain reaction (RT-PCR) was used to screen 86 samples. Viral protein 1 (VP1) codon sequencing was performed. The virus was isolated from the samples inoculated on

SUBMITTER: Shahein MA 

PROVIDER: S-EPMC10446720 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature