Dataset Information

Functional and structural impairments of the pulmonary system in middle-aged people with cervical and upper thoracic spinal cord injuries.

ABSTRACT:

Objectives

To describe functional and structural impairments of the pulmonary system in middle-aged people with cervical and upper thoracic spinal cord injuries (SCI), and compare findings to the general population. To determine if the neurological level of injury (NLI) is related to functional and structural impairments, and if age is related to structural impairments.

Design

Cross-sectional study with matched controls. Data from the Swedish SPinal Cord Injury Study on Cardiopulmonary and Autonomic Impairment (SPICA). Matched control data were obtained from the Swedish CArdioPulmonary bioImage Study (SCAPIS).

Setting

Outpatient SCI unit in southern Sweden.

Participants

25 people (20% women, mean age 58 years, mean time since injury 28 years, NLIs C2-T6, American Spinal Injury Association Impairment Scale A-C).

Interventions

Not applicable.

Outcome measures

Lung function was assessed with spirometry, diffusing capacity and impulse oscillometry. Structural assessments were performed with computed tomography.

Results

Pulmonary function was generally worse compared to the controls. Structural impairments were common (75% of the participants and 65% of the controls; P = 0.36, NS). NLI was significantly related to some of the functional and structural impairments.

Conclusions

Middle-aged people with long-term cervical and upper thoracic SCI can have substantial pulmonary functional impairments, whereas structural impairments do not differ considerably from the general population. Further larger and longitudinal studies should focus on the clinical impact of these impairments over time.

SUBMITTER: Hill M

PROVIDER: S-EPMC10446799 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Functional and structural impairments of the pulmonary system in middle-aged people with cervical and upper thoracic spinal cord injuries.

Hill Mattias M Jörgensen Sophie S Engström Gunnar G Persson Margaretha M Wollmer Per P Lexell Jan J

The journal of spinal cord medicine 20220223 5

<h4>Objectives</h4>To describe functional and structural impairments of the pulmonary system in middle-aged people with cervical and upper thoracic spinal cord injuries (SCI), and compare findings to the general population. To determine if the neurological level of injury (NLI) is related to functional and structural impairments, and if age is related to structural impairments.<h4>Design</h4>Cross-sectional study with matched controls. Data from the Swedish SPinal Cord Injury Study on Cardiopulm ...[more]

PMID: 35196208

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Dataset Information

Functional and structural impairments of the pulmonary system in middle-aged people with cervical and upper thoracic spinal cord injuries.

Objectives

Design

Setting

Participants

Interventions

Outcome measures

Results

Conclusions

Publications

Functional and structural impairments of the pulmonary system in middle-aged people with cervical and upper thoracic spinal cord injuries.

Similar Datasets

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