Terbinafine-Resistant Dermatophytes and the Presence of Trichophyton indotineae in North America.

ABSTRACT: Dermatophytes are common causes of skin, hair, and nail infections in humans. The most common species causing infections in humans are Trichophyton rubrum, Trichophyton mentagrophytes, and Trichophyton interdigitale. Outbreaks of recalcitrant dermatophytosis have been reported in parts of South Asia, including those caused by a hypervirulent and resistant species, Trichophyton indotineae. We evaluated the antifungal susceptibility profiles of dermatophytes received by our laboratory from institutions across North America between 2021 and 2022 and performed species identification for isolates deemed to demonstrate in vitro resistance. Susceptibility testing was performed by CLSI broth microdilution methods, and species identification was performed by DNA sequence analysis. During thi

SUBMITTER: Canete-Gibas CF 

PROVIDER: S-EPMC10446870 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature