Toxicological and histopathological alterations in the heart of young and adult albino rats exposed to mosquito coil smoke.

ABSTRACT: Mosquito coil repellents are well-known indoor air pollutant with significant health concerns. The present study investigated the toxic effects of mosquito coil smoke on the heart of young and adult male rats. The animals were subjected to the smoke for 6 h/day, 6 days/week, for 4 weeks. Within the first hour after lighting the coil, significant amounts of formaldehyde, total volatile organic compounds, and particulate matter (PM2.5 and PM10) were detected. Both exposed ages, particularly the young group, showed a significant increase in the activities of serum aspartate aminotransferase, lactate dehydrogenase, creatine kinase-MB, and the levels of troponin I, myoglobin, Na⁺ levels, lipid profile, and inflammatory markers (interleukin-6 and C-reactive protein) as well as a signi

SUBMITTER: Abdrabouh AE 

PROVIDER: S-EPMC10447284 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature