Measuring dengue illness intensity: Development and content validity of the dengue virus daily diary (DENV-DD).

ABSTRACT:

Background

Dengue is the most prevalent arboviral infection causing an estimated 50-60 million cases of febrile illness globally per year, exacting considerable disease burden. Few instruments exist to assess the patient illness experience, with most based on healthcare provider assessment, lacking standardization in timepoints and symptom assessment. This study aimed to evaluate the content validity of the novel 'Dengue Virus Daily Diary (DENV-DD)', designed to measure symptom intensity and disease burden within outpatient infant to adult populations.

Methods

The Dengue Illness Index Report Card was used as a foundation to create the DENV-DD, consisting of patient- and observer-reported outcome (PRO/ObsRO) instruments. In two South American dengue-endemic communities, quali

SUBMITTER: Jones AM 

PROVIDER: S-EPMC10447358 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature