Flavonoid intake and survival after diagnosis of colorectal cancer: a prospective study in 2 US cohorts.

ABSTRACT:

Background

Although experimental evidence supports anticancer effects of flavonoids, the influence of flavonoid intake on colorectal cancer (CRC) survival remains unknown.

Objectives

This study aimed to assess the association of postdiagnostic flavonoid intake with mortality.

Methods

We prospectively assessed the association of postdiagnostic flavonoid intake with CRC-specific and all-cause mortality in 2552 patients diagnosed with stage I-III CRC in 2 cohort studies-the Nurses' Health Study and the Health Professionals Follow-up Study. We assessed the intake of total flavonoids and their subclasses using validated food frequency questionnaires. We used the inverse probability-weighted multivariable Cox proportional hazards regression model to calculate the hazard rat

SUBMITTER: Shi S 

PROVIDER: S-EPMC10447476 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature