Comparison of an Initial Risk-Based Testing Strategy vs Usual Testing in Stable Symptomatic Patients With Suspected Coronary Artery Disease: The PRECISE Randomized Clinical Trial.

ABSTRACT:

Importance

Trials showing equivalent or better outcomes with initial evaluation using coronary computed tomography angiography (cCTA) compared with stress testing in patients with stable chest pain have informed guidelines but raise questions about overtesting and excess catheterization.

Objective

To test a modified initial cCTA strategy designed to improve clinical efficiency vs usual testing (UT).

Design, setting, and participants

This was a pragmatic randomized clinical trial enrolling participants from December 3, 2018, to May 18, 2021, with a median of 11.8 months of follow-up. Patients from 65 North American and European sites with stable symptoms of suspected coronary artery disease (CAD) and no prior testing were randomly assigned 1:1 to precision strategy (PS

SUBMITTER: Douglas PS 

PROVIDER: S-EPMC10448364 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature