Coronary Venous Pressure and Microvascular Hemodynamics in Patients With Microvascular Angina: A Randomized Clinical Trial.

ABSTRACT:

Importance

The role of the coronary venous circulation in regulating myocardial perfusion and its potential in treating microvascular angina is unexplored.

Objective

To evaluate whether an increase in coronary venous pressure modifies microvascular resistance in patients with microvascular angina.

Design, setting, and participants

This was a blinded, sham-controlled, crossover, randomized clinical trial that enrolled participants between November 2021 and January 2023. Participants for this physiology end point study were recruited from the Cardiology Center of the University of Medicine in Mainz, Germany. Patients with moderate/severe angina pectoris (Canadian Cardiovascular Society class 2-4) due to microvascular dysfunction (as defined by the thermodilution-based i

SUBMITTER: Ullrich H 

PROVIDER: S-EPMC10448373 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature