Characterization of C₃₀ carotenoid and identification of its biosynthetic gene cluster in Methylobacterium extorquens AM1.

ABSTRACT: Methylobacterium species, the representative bacteria distributed in phyllosphere region of plants, often synthesize carotenoids to resist harmful UV radiations. Methylobacterium extorquens is known to produce a carotenoid pigment and recent research revealed that this carotenoid has a C₃₀ backbone. However, its exact structure remains unknown. In the present study, the carotenoid produced by M. extorquens AM1 was isolated and its structure was determined as 4-[2-O-11Z-octadecenoyl-β-glucopyranosyl]-4,4'-diapolycopenedioc acid (1), a glycosylated C₃₀ carotenoid. Furthermore, the genes related to the C₃₀ carotenoid synthesis were investigated. Squalene, the precursor of the C₃₀ carotenoid, is synthesized b

SUBMITTER: Mo XH 

PROVIDER: S-EPMC10448405 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature