Body Position and Orthostatic Hypotension in Hypertensive Adults: Results from the Syst-Eur Trial.

ABSTRACT:

Background

We recently demonstrated that more intensive blood pressure (BP) treatment lowered risk of orthostatic hypotension (OH) measured with a seated-to-standing protocol. However, seated-to-standing OH assessments are less sensitive than supine-to-standing and could miss clinically relevant OH.

Objectives

Using data from the Syst-Eur trial (Systolic Hypertension in Europe), we examined the effect of hypertension treatment on incidence of OH based on the difference in BP from 3 body positions.

Methods

Syst-Eur was a multi-center, randomized trial that enrolled adults with isolated systolic hypertension to investigate whether active hypertension treatment could reduce cardiovascular events. Participants underwent BP measurement in supine, seated, and standing posit

SUBMITTER: Grobman B 

PROVIDER: S-EPMC10448480 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature