Identification of potential angiogenic biomarkers in human follicular fluid for predicting oocyte maturity.

ABSTRACT:

Background

Angiogenesis in folliculogenesis contributes to oocyte developmental competence in natural and in vitro fertilization (IVF) cycles. Therefore, the identification of key angiogenic factors in follicular fluid (FF) during folliculogenesis is clinically significant and important for in vitro fertilization. This study aims to identify the key angiogenic factors in FF for predicting oocyte maturity during in vitro fertilization.

Materials and methods

Forty participants who received ovarian stimulation using a GnRH antagonist protocol in their first in vitro fertilization treatment were recruited. From each patient, two follicular samples (one preovulatory follicle, > 18 mm; one mid-antral follicle, < 14 mm) were collected without flushing du

SUBMITTER: Chen HT 

PROVIDER: S-EPMC10448508 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature