Infant sex at birth and long-term maternal mortality.

ABSTRACT:

Background

Maternal adaptations may vary by foetal sex. Whether male infants influence long-term mortality in mothers remains uncertain.

Objective

The objective of the study was to examine whether male infants increase the risk of maternal mortality.

Methods

This study included pregnant women enrolled at 12 US sites from 1959 to 1966 in the Collaborative Perinatal Project (CPP). Collaborative Perinatal Project records were linked to the National Death Index and the Social Security Master Death File to ascertain deaths until 2016. Foetal sex was determined by infant sex at birth, defined as the total number of male or female infants in pregnancies prior to or during enrolment in the CPP. In secondary analyses, exposure was defined as infant sex at the last CPP delivery

SUBMITTER: Grandi SM 

PROVIDER: S-EPMC10448630 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature