Prognostic role of euthyroid sick syndrome in MIS-C: results from a single-center observational study

ABSTRACT:

Background

Euthyroid sick syndrome (ESS) is characterized by low serum levels of free triiodothyronine (fT3) with normal or low levels of thyroid stimulating hormone (TSH) and free thyroxine (fT4) and is reported in different acute clinical situations, such as sepsis, diabetic ketoacidosis and after cardiac surgery. Our aim was to evaluate the predicting role of ESS for disease severity in patients with Multisystem Inflammatory Syndrome in children (MIS-C).

Methods

A single-centre observational study on consecutive patients with MIS-C. Before treatment clinical, and laboratory data were collected and, in a subset of patients, thyroid function tests were repeated 4 weeks later. Variables distribution was analyzed by Mann-Whitney U-test and correlations between different pa

SUBMITTER: Fastiggi M 

PROVIDER: S-EPMC10448823 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature