Habitual intake of fat and sugar is associated with poorer memory and greater impulsivity in humans.

ABSTRACT: The vicious cycle model of obesity suggests that repeated habitual intake of a diet high in fat and sugar (HFS) results in impairment in hippocampal function which in turn increases impulsive behaviours, making it harder to resist unhealthy diet choices. Evidence from studies with rodents consistently show switching to a HFS diet impairs performance on hippocampally-sensitive memory tasks. The limited literature in humans also suggest impaired memory and increased impulsivity related to higher habitual HFS intake. However, these changes in memory and impulsivity have been looked at independently. To investigate how these effects are inter-related, three experiments were conducted where relative HFS intake was related to measures of memory and impulsivity. In Experiment 1 (90 female partici

SUBMITTER: Yeomans MR 

PROVIDER: S-EPMC10449134 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature