Serosim: An R package for simulating serological data arising from vaccination, epidemiological and antibody kinetics processes.

ABSTRACT: serosim is an open-source R package designed to aid inference from serological studies, by simulating data arising from user-specified vaccine and antibody kinetics processes using a random effects model. Serological data are used to assess population immunity by directly measuring individuals' antibody titers. They uncover locations and/or populations which are susceptible and provide evidence of past infection or vaccination to help inform public health measures and surveillance. Both serological data and new analytical techniques used to interpret them are increasingly widespread. This creates a need for tools to simulate serological studies and the processes underlying observed titer values, as this will enable researchers to identify best practices for serological study design, and pr

SUBMITTER: Menezes A 

PROVIDER: S-EPMC10449138 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature