Presurgical microstructural coherence predicts cognitive change for bariatric surgery patients.

ABSTRACT:

Objective

This observational study examined the relationship between presurgical white matter microstructural coherence and cognitive change after weight loss. It was hypothesized that higher baseline fractional anisotropy (FA) would predict greater baseline and change cognition.

Methods

A sample of 24 adults (BMI ≥ 35 kg/m² ) underwent neuropsychological assessment at baseline and 12 weeks after bariatric surgery. A magnetic resonance imaging brain scan was administered at baseline and processed through Tract-Based Spatial Statistics to compute FA in white matter tracts of interest. Composite scores for attention, learning, processing speed, executive function, verbal fluency, working memory, and overall cognition were calculated.

Results

As expected, FA i

SUBMITTER: Chen AK 

PROVIDER: S-EPMC10449364 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature