Genomics and inclusion of Indigenous peoples in high income countries.

ABSTRACT: Genomics research related to Indigenous people has been at worst exploitative and at best, retrospectively on a journey to improve effective engagement of Indigenous individuals and communities. Genomics can positively impact all stages of clinical management, and to improve genomic effectiveness researchers aggregate genomic data from diverse global sub-populations, such as shared ancestry groupings, as people within these groupings will have a greater proportion of shared DNA traits. While genomics is already being used worldwide to improve lives, its utility and effectiveness has not been maximized for individuals with Indigenous ancestry. Several large datasets of human genetic variation have been made publicly available, of which the most widely used is the Genome Aggregation Database

SUBMITTER: Gwynne K 

PROVIDER: S-EPMC10449672 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature