Exposure to benzene and other hydrocarbons and risk of bladder cancer among male offshore petroleum workers.

ABSTRACT:

Background

Occupational exposures constitute the second leading cause of urinary bladder cancer after tobacco smoking. Increased risks have been found in the petroleum industry, but high-quality exposure data are needed to explain these observations.

Methods

Using a prospective case-cohort design, we analysed 189 bladder cancer cases (1999-2017) and 2065 randomly drawn non-cases from the Norwegian Offshore Petroleum Workers cohort. Cases were identified in the Cancer Registry of Norway, while work histories (1965-1998) and lifestyle factors were recorded by questionnaire at baseline (1998). Occupational petroleum-related hydrocarbon exposures were assessed by expert-developed job-exposure matrices. Hazard ratios were estimated by weighted Cox-regressions, adjusted for age, t

SUBMITTER: Shala NK 

PROVIDER: S-EPMC10449774 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature