Clinical features of COVID-19 in Italian outpatient children and adolescents during Parental, Delta, and Omicron waves: a prospective, observational, cohort study.

ABSTRACT:

Introduction

COVID-19 features changed with the Omicron variant of SARS-CoV-2 in adults. This study aims to describe COVID-19 symptoms in children and adolescents during the Parental, Delta, and Omicron eras.

Methods

A single-centre, prospective observational study was conducted on individuals aged 0-20 years attending the University Hospital of Padua (Italy) from April 2020 to December 2022. COVID-19 cases were defined by positive SARS-CoV-2 molecular detection and/or serology; patient/family symptoms and virological positivity were considered to determine the infection onset. Variables were summarized and compared using appropriate tests of descriptive statistics.

Results

A total of 509 cases [46% female, median age eight years (IQR: 4-12)] were studied. Three-hundr

SUBMITTER: Di Chiara C 

PROVIDER: S-EPMC10450148 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature