Hyperoxia is associated with a greater risk for mortality in critically ill traumatic brain injury patients than in critically ill trauma patients without brain injury.

ABSTRACT:

Objective

The role of hyperoxia in patients with traumatic brain injury (TBI) remains controversial. The objective of this study was to determine the association between hyperoxia and mortality in critically ill TBI patients compared to critically ill trauma patients without TBI.

Design

Secondary analysis of a multicenter retrospective cohort study.

Setting

Three regional trauma centers in Colorado, USA, between October 1, 2015, and June 30, 2018.

Patients

We included 3464 critically injured adults who were admitted to an intensive care unit (ICU) within 24 h of arrival and qualified for inclusion into the state trauma registry. We analyzed all available SpO2 values during the first seven ICU days. The primary outcome was in-hospital mortality. Secondary outcom

SUBMITTER: Douin DJ 

PROVIDER: S-EPMC10450323 | biostudies-literature | 2023 Jan-Mar

REPOSITORIES: biostudies-literature