Sleep Deprivation-Induced Oxidative Stress in Rat Models: A Scoping Systematic Review.

ABSTRACT: Sleep deprivation is highly prevalent in the modern world, possibly reaching epidemic proportions. While multiple theories regarding the roles of sleep exist (inactivity, energy conservation, restoration, brain plasticity and antioxidant), multiple unknowns still remain regarding the proposed antioxidant roles of sleep. The existing experimental evidence is often contradicting, with studies pointing both toward and against the presence of oxidative stress after sleep deprivation. The main goals of this review were to analyze the existing experimental data regarding the relationship between sleep deprivation and oxidative stress, to attempt to further clarify multiple aspects surrounding this relationship and to identify current knowledge gaps. Systematic searches were conducted in three ma

SUBMITTER: Neculicioiu VS 

PROVIDER: S-EPMC10451248 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature