Ontology highlight
ABSTRACT:
SUBMITTER: Brackhan M
PROVIDER: S-EPMC10451380 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature
Brackhan Mirjam M Arribas-Blazquez Marina M Lastres-Becker Isabel I
Antioxidants (Basel, Switzerland) 20230804 8
Although the trigger for the neurodegenerative disease process is unknown, the relevance of aging stands out as a major risk for the development of neurodegeneration. In this review, we highlighted the relationship between the different cellular mechanisms that occur as a consequence of aging and transcription factor nuclear factor erythroid-2-related factor 2 (NRF2) and the connection with the TAU protein. We focused on the relevance of NRF2 in the main processes involved in neurodegeneration a ...[more]