Molecular Mechanisms of Endometriosis Revealed Using Omics Data.

ABSTRACT: Endometriosis is a gynecological disorder prevalent in women of reproductive age. The primary symptoms include dysmenorrhea, irregular menstruation, and infertility. However, the pathogenesis of endometriosis remains unclear. With the advent of high-throughput technologies, various omics experiments have been conducted to identify genes related to the pathophysiology of endometriosis. This review highlights the molecular mechanisms underlying endometriosis using omics. When genes identified in omics experiments were compared with endometriosis disease genes identified in independent studies, the number of overlapping genes was moderate. However, the characteristics of these genes were found to be equivalent when functional gene set enrichment analysis was performed using gene ontology and

SUBMITTER: Cho SB 

PROVIDER: S-EPMC10452455 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature