Alterations of large-scale functional network connectivity in patients with infantile esotropia before and after surgery.

ABSTRACT:

Background

Growing evidences have indicated neurodevelopmental disorders in infantile esotropia (IE). However, few studies have analyzed the characteristics of large-scale functional networks of IE patients or their postoperative network-level alterations.

Methods

Here, individuals with IE (n = 32) and healthy subjects (n = 30) accomplished the baseline clinical examinations and resting-state MRI scans. A total of 17 IE patients also underwent corrective surgeries and completed the longitudinal clinical assessments and resting-state MRI scans. Linear mixed effects models were applied for cross-sectional and longitudinal network-level analyses. Correlation analysis was performed to assess the relationship between longitudinal functional connectivity (FC) alterations and basel

SUBMITTER: Guo J 

PROVIDER: S-EPMC10454265 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature