Spatial patterns of intrinsic brain activity in rats with capsular stroke.

ABSTRACT:

Background

To explore the neural changes of brain activity in rats with circumscribed capsular infarcts to find a new therapeutic target for promoting the functional recovery.

Methods

A total of 18 capsular infarct rats and 18 normal rats were conducted in this study. All animal use procedures were strictly in accordance with the guide for the care and use of laboratory animals. After establishing the photothrombotic capsular infarct model, the functional magnetic resonance imaging (fMRI) data were collected and analyzed.

Results

The fMRI results indicated that the passive movement would induce strong activation in caudate, putamen, frontal association somatosensory cortex, thalamus dorsolateral, and thalamus midline dorsal in control group, and the passive movement w

SUBMITTER: Ma J 

PROVIDER: S-EPMC10454278 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature