Antimicrobial Peptides Demonstrate Activity against Resistant Bacterial Pathogens.

ABSTRACT: The antimicrobial resistance crisis is an ongoing major threat to public health safety. Low- and middle-income countries are particularly susceptible to higher fatality rates and the economic impact of antimicrobial resistance (AMR). As an increasing number of pathogens emerge with multi- and pan-drug resistance to last-resort antibiotics, there is an urgent need to provide alternative antibacterial options to mitigate disease transmission, morbidity, and mortality. As identified by the World Health Organization (WHO), critically important pathogens such as Klebsiella and Pseudomonas species are becoming resistant to last-resort antibiotics including colistin while being frequently isolated from clinical cases of infection. Antimicrobial peptides are potent amino acid sequenc

SUBMITTER: Garvey M 

PROVIDER: S-EPMC10454446 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature