Prostate Cancer: Genetics, Epigenetics and the Need for Immunological Biomarkers.

ABSTRACT: Epidemiological data highlight prostate cancer as a significant global health issue, with high incidence and substantial impact on patients' quality of life. The prevalence of this disease is associated with various factors, including age, heredity, and race. Recent research in prostate cancer genetics has identified several genetic variants that may be associated with an increased risk of developing the disease. However, despite the significance of these findings, genetic markers for prostate cancer are not currently utilized in clinical practice as reliable indicators of the disease. In addition to genetics, epigenetic alterations also play a crucial role in prostate cancer development. Aberrant DNA methylation, changes in chromatin structure, and microRNA (miRNA) expression are major ep

SUBMITTER: Rafikova G 

PROVIDER: S-EPMC10454494 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature