SsCak1 Regulates Growth and Pathogenicity in Sclerotinia sclerotiorum.

ABSTRACT: Sclerotinia sclerotiorum is a devastating fungal pathogen that causes severe crop losses worldwide. It is of vital importance to understand its pathogenic mechanism for disease control. Through a forward genetic screen combined with next-generation sequencing, a putative protein kinase, SsCak1, was found to be involved in the growth and pathogenicity of S. sclerotiorum. Knockout and complementation experiments confirmed that deletions in SsCak1 caused defects in mycelium and sclerotia development, as well as appressoria formation and host penetration, leading to complete loss of virulence. These findings suggest that SsCak1 is essential for the growth, development, and pathogenicity of S. sclerotiorum. Therefore, SsCak1 could serve as a pote

SUBMITTER: Qin L 

PROVIDER: S-EPMC10454577 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature