Association between interleukin-1 alpha rs1800587 polymorphism and rheumatoid arthritis: A meta-analysis.

ABSTRACT: No consistent results have been reached on the relationship of interleukin-1 (IL-1) rs1800587 polymorphism with the susceptibility to rheumatoid arthritis (RA) so far. Therefore, the current meta-analysis was designed to thoroughly review relevant studies, in order to examine the relationship of IL-1A rs1800587 polymorphism with RA risk. Electronic databases were retrieved for literature regarding the relationship between IL-1A rs1800587 polymorphism and RA vulnerability according to the inclusion and exclusion criteria. Stata 12.0 software was adopted to examine the enrolled literature. Meanwhile, odds ratio (OR) and corresponding 95% confidence intervals (95% CI) were used to evaluate the association. A total of seven case-control researches (3267 patients and 2960 healthy controls) were

SUBMITTER: Wang H 

PROVIDER: S-EPMC10455026 | biostudies-literature | 2021 Apr-Jun

REPOSITORIES: biostudies-literature