Trends in the Epidemiology of Pneumocystis Pneumonia in Immunocompromised Patients without HIV Infection.

ABSTRACT: The increasing morbidity and mortality of life-threatening Pneumocystis pneumonia (PCP) in immunocompromised people poses a global concern, prompting the World Health Organization to list it as one of the 19 priority invasive fungal diseases, calling for increased research and public health action. In response to this initiative, we provide this review on the epidemiology of PCP in non-HIV patients with various immunodeficient conditions, including the use of immunosuppressive agents, cancer therapies, solid organ and stem cell transplantation, autoimmune and inflammatory diseases, inherited or primary immunodeficiencies, and COVID-19. Special attention is given to the molecular epidemiology of PCP outbreaks in solid organ transplant recipients; the risk of PCP associated with the i

SUBMITTER: Xue T 

PROVIDER: S-EPMC10455156 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature