The Intricate Role of Ecdysis Triggering Hormone Signaling in Insect Development and Reproductive Regulation.

ABSTRACT: Insect growth is interrupted by molts, during which the insect develops a new exoskeleton. The exoskeleton confers protection and undergoes shedding between each developmental stage through an evolutionarily conserved and ordered sequence of behaviors, collectively referred to as ecdysis. Ecdysis is triggered by Ecdysis triggering hormone (ETH) synthesized and secreted from peripheral Inka cells on the tracheal surface and plays a vital role in the orchestration of ecdysis in insects and possibly in other arthropod species. ETH synthesized by Inka cells then binds to ETH receptor (ETHR) present on the peptidergic neurons in the central nervous system (CNS) to facilitate synthesis of various other neuropeptides involved in ecdysis. The mechanism of ETH function on ecdysis has been well inve

SUBMITTER: Malhotra P 

PROVIDER: S-EPMC10455322 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature