The State of the Art in Transcriptomics and Proteomics of Clinically Relevant Sporothrix Species.

ABSTRACT: Proteomics provide a robust approach to profile and quantify proteins within cells, organs, or tissues, providing comprehensive insights about the dynamics of cellular processes, modifications, and interactions. Similarly, understanding the transcriptome is essential to decipher functional elements of the genome, unraveling the mechanisms of disease development and the molecular constituents of cells and tissues. Some thermodimorphic fungi of the genus Sporothrix cause sporotrichosis, a subcutaneous mycosis of worldwide relevance. The transcriptome and proteome of the main Sporothrix species of clinical interest can elucidate the mechanisms underlying pathogenesis and host interactions. Studies of these techniques can contribute to the advancement of novel diagnostic and ther

SUBMITTER: Procopio-Azevedo AC 

PROVIDER: S-EPMC10455387 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature