Marine-Derived Components: Can They Be a Potential Therapeutic Approach to Parkinson's Disease?

ABSTRACT: The increase in the life expectancy average has led to a growing elderly population, thus leading to a prevalence of neurodegenerative disorders, such as Parkinson's disease (PD). PD is the second most common neurodegenerative disorder and is characterized by a progressive degeneration of the dopaminergic neurons in the substantia nigra pars compacta (SNpc). The marine environment has proven to be a source of unique and diverse chemical structures with great therapeutic potential to be used in the treatment of several pathologies, including neurodegenerative impairments. This review is focused on compounds isolated from marine organisms with neuroprotective activities on in vitro and in vivo models based on their chemical structures, taxonomy, neuroprotective effects, and their poss

SUBMITTER: Silva J 

PROVIDER: S-EPMC10455662 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature