Ontology highlight
ABSTRACT:
SUBMITTER: Hong WC
PROVIDER: S-EPMC10455843 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature
Hong Woosol Chris WC Lee Da Eun DE Kang Hyeon Woong HW Kim Myeong Jin MJ Kim Minsoo M Kim Ju Hyun JH Fang Sungsoon S Kim Hyo Jung HJ Park Joon Seong JS
International journal of molecular sciences 20230820 16
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive form of pancreatic cancer with a poor prognosis and low survival rates. The prognostic and predictive biomarkers of PDAC are still largely unknown. The receptor CD74 was recently identified as a regulator of oncogenic properties in various cancers. However, the precise molecular mechanism of CD74 action in PDAC remains little understood. We investigated the role of CD74 by silencing CD74 in the pancreatic cancer cell line Capan-1. CD74 kno ...[more]