Whole-Body Cryotherapy Alters Circulating MicroRNA Profile in Postmenopausal Women.

ABSTRACT: The incidence of metabolic syndrome (MetS) increases with age, especially in women. The role of microRNAs (miRs) in the regulation of metabolism is postulated. The aim of the study is to identify miRs that may be markers of MetS and to assess changes in miRs expression as a result of 10 and 20 whole-body cryotherapy treatments (WBC; 3 min, -120 °C) in postmenopausal women with MetS (M-60, BMI 30.56 ± 5.38 kg/m²), compared to healthy postmenopausal (H-60, BMI 25.57 ± 2.46 kg/m²) and healthy young women (H-20, BMI 22.90 ± 3.19 kg/m²). In a fasting state, before 1 WBC and after 10 WBCs, as well as 20 WBCs, the expression of miR-15a-5p, miR-21-5p, miR-23a-3p, miR-146a-5p, miR-197-3p, miR-223-3p, fasting blood glucose (FBG) and blood lipid profile were determine

SUBMITTER: Wiecek M 

PROVIDER: S-EPMC10455963 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature