Uniaxial Cyclic Cell Stretching Device for Accelerating Cellular Studies.

ABSTRACT: Cellular response to mechanical stimuli is a crucial factor for maintaining cell homeostasis. The interaction between the extracellular matrix and mechanical stress plays a significant role in organizing the cytoskeleton and aligning cells. Tools that apply mechanical forces to cells and tissues, as well as those capable of measuring the mechanical properties of biological cells, have greatly contributed to our understanding of fundamental mechanobiology. These tools have been extensively employed to unveil the substantial influence of mechanical cues on the development and progression of various diseases. In this report, we present an economical and high-performance uniaxial cell stretching device. This paper reports the detailed operation concept of the device, experimental design, and c

SUBMITTER: Yadav S 

PROVIDER: S-EPMC10456305 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature